Patients ask one question more than any other: when will it stop hurting? Here is the honest timeline, week by week.
In short: Acute fissure: 2 to 6 weeks with soft stools. Chronic fissure on nifedipine or diltiazem: pain improves in 1 to 2 weeks, closure in 6 to 8 weeks in 50 to 70 % of cases. After surgery: 2 to 4 weeks.
Medically reviewed by Dra. Milagros Carla Quinto Cobeña, Cirugía general, especialista en proctología · CMP 53588 · RNE 30074 · Clínica Proctológica de Lima · Updated 2026-11-01
Week by week on a sphincter-relaxing protocol
Week
What usually happens
1
Less spasm; bowel movements still hurt but the pain after them shortens. Stools must already be soft.
2
Pain during stool clearly lower in most patients; bleeding becomes occasional.
3–4
Many acute fissures are closed. Chronic ones: pink tissue at the base, less bleeding. Check-up with the surgeon.
5–6
Pain gone or minimal; the tear is closing from the edges.
7–8
Most chronic fissures that are going to close with cream have closed. If not, discuss Botox or surgery.
What speeds healing (and what slows it)
Helps
Psyllium 2 times a day and 2 liters of water
Sitz baths after every stool
Applying the cream on schedule, every day, for the full course
Not holding stool in
Slows
Stopping the cream when pain improves (week 2)
Straining and long time on the toilet
Wiping hard; use water instead
Steroid creams for weeks
Frequently asked questions
The pain is gone at week 2. Can I stop?
No. Pain disappears before the tear closes. Stopping early is the most common reason fissures come back. Complete the course.
This content is educational and does not replace a medical consultation. FISURIN is a magistral (compounded) formula prepared under prescription in an authorized pharmacy; availability and regulatory status vary by country. If you have bleeding that does not stop, fever, or pain that worsens, seek medical care without delay.
